SysCall is a logistic regression based classifier. Given a list of candidate heterozygous genomic locations and a sam file of sequenced reads SysCall classifies each genomic location as either a heterozygous site or a systematic error and outputs according lists, along with the assigned posterior probabilities.
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F Meacham, D Boffelli, J Dhahbi, DI Martin, M Singer and L Pachter
Identification and correction of systematic error in high-throughput sequence data
BMC Bioinformatics 2011, 12:451 doi:10.1186/1471-2105-12-451