ParaSAM is a high performance parallel processing implementation of the SAM (Significance Analysis of Microarrays) algorithm. The permutations are divided across the multiple nodes. The computational workload is divided among multiple CPUs and the main memory of all participating computers is utilized to avoid caching operations to the disk, which significantly decrease algorithm execution time.
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If you don’t want to install ParaSAM locally, you can use a Web version here.
If you make use of the program presented here, please cite the following article:
Sharma A, Zhao J, Podolsky R, McIndoe RA: ParaSAM: A parallelized version of the significance analysis of microarrays algorithm. Bioinformatics 2010.