MLOGD (Maximum Likelihood Overlapping Gene Detector) is a suite of software for detecting new protein-coding sequences (CDSs) by analysing the pattern of mutations across an input sequence alignment. In particular, the software can be used to detect new CDSs that overlap known CDSs in a different read-frame. Such CDSs can be difficult to detect with standard gene-finding algorithms (see below). The software is particularly useful for analysing virus genome alignments, where overlapping genes and ribosomal frameshifting sites are common.
- Linux / MacOsX
- C++ Compiler
- R Package
:: MORE INFORMATION
Firth A. E., Brown C. M., 2006,
Detecting Overlapping Coding Sequences in Virus Genomes,
BMC Bioinformatics, 7, 75.