The SBT (Sequence Bloom Tree) is a method that will allow you to index a set of short-read sequencing experiments and then query them quickly for a given sequence.
HowDeSBT is a data structure, which uses a novel partitioning of information to reduce the construction and query time as well as the size of the index.
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Bioinformatics, 36 (3), 721-727 2020 Feb 1
Improved Representation of Sequence Bloom Trees
Robert S Harris , Paul Medvedev