ANCESCON is a package for distance-based phylogenetic inference and reconstruction of ancestral protein sequences that takes into account the observed variation of evolutionary rates between positions that more precisely describes the evolution of protein families.
:: MORE INFORMATION
W.Cai, J.Pei, and N.V.Grishin (2004)
“Reconstruction of ancestral protein sequences and its applications“.
BMC Evolutionary Biology 4(1): 33