ZifNet is the package that can be used to predict the DNA binding model for any given a C2H2 zinc finger based on back-propagation algorithm. It includes two parts: First, identify the optimal DNA-zinc finger interaction model with the core C programs of ZifNet. And second, predict DNA-binding weight matrix models for Zinc fingers using the auxiliary codes, and the defined DNA-zinc finger interaction model derived from the last step.
Stormo Lab in Department of Genetics, Washington University
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