XQTL is a family-based allelic/haplotype association test for quantitative traits using X-linked SNP/two-locus markers in a nuclear family design. XQTL adopts the framework of the orthogonal model implemented in the QTDT program with modification of the sex-specific score for X-linked genotypes. XQTL also takes into account the dosage effect due to female X chromosome inactivation.
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Zhang L, Martin ER, Morris RW, Li YJ. (2009)
Association test for X-linked QTL in family-base d designs.
American Journal of Human Genetics