VIP (Variant Identification by Pooling)is a complete data analysis framework for overlapping pool design. It is very flexible and can be combined with any pool design approaches and sequence mapping/alignment tools.
Computational Biology lab @ Case (CBC)
- Linux / Windows
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Bioinformatics. 2013 Jan 1;29(1):29-38. doi: 10.1093/bioinformatics/bts645. Epub 2012 Oct 27.
Rare variant discovery and calling by sequencing pooled samples with overlaps.
Wang W1, Yin X, Soo Pyon Y, Hayes M, Li J.