Velvet is a de novo genomic assembler specially designed for short read sequencing technologies, such as Solexa or 454.Velvet currently takes in short read sequences, removes errors then produces high quality unique contigs. It then uses paired-end read and long read information, when available, to retrieve the repeated areas between contigs.
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D.R. Zerbino and E. Birney.
Velvet: algorithms for de novo short read assembly using de Bruijn graphs.
Genome Research 18:821-829.