TRFolder / TRFolder-W – Telomerase RNA Structure Prediction

TRFolder /  TRFolder-W


TRFolder is a utility program capable of searching for the core structure (including pseudoknots and triple helices) of telomerase RNAs. It consists of a set of functions for telomerase RNA (TR) specific structure prediction. Unlike existing general purpose structure prediction programs, TRFolder works progressively to predict core TR elements pseudoknots, triple helices, telomere repeat template boundary elements, and core-closing stems that occur in TRs.


The RNA-Informatics Research Lab




  • Windows / MacOsX / Linux
  • C++ Complier
  • Python





Bioinformatics. 2012 Oct 15;28(20):2696-7. doi: 10.1093/bioinformatics/bts506. Epub 2012 Aug 24.
TRFolder-W: a web server for telomerase RNA structure prediction in yeast genomes.
Zhang D1, Xue X, Malmberg RL, Cai L.

Guo, L., Zhang, D., Wang, Y., Malmberg, R., McEachern, M., and Cai, L. (2011)
TRFolder: Computational prediction of novel telomerase RNAs in yeast genomes
Int J Bioinform Res Appl. 2011;7(1):63-81.

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