TreeFit evaluates how well a UPGMA or neighbor-joining tree fits a genetic distance matrix.TreeFit was written to analyze how well a tree fits the genetic data the tree was calculated from. TreeFit creates neighbor-joining and UPGMA trees from a genetic distance matrix, and then compares the observed genetic distance between populations with the genetic distance in the tree. The similarity between these distances is express as R-squared, the familiar statistic used to summarize the scatter of points around a least-squares regression line.
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KALINOWSI ST (2009)
How well do evolutionary trees describe genetic relationships between populations?