TREAT ( Targeted RE-sequencing Annotation Tool) offers an comprehensive, open framework, end-to-end solution for analyzing and interpreting targeted re-sequencing data. TREAT encompasses sequence alignment, variant calling, variant annotation, variant filtering, and visualization in one comprehensive analytic workflow. The rich set of annotations provided by TREAT enables the filtering of detected variants based on their functional characteristics, and visualizations at the variant positions allow the investigators to closely examine the identified variants of interest
Bioinformatics Program, Division of Biomedical Statistics and Informatics, Mayo Clinic Research
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TREAT: a bioinformatics tool for variant annotations and visualizations in targeted and exome sequencing data.
Asmann YW, Middha S, Hossain A, Baheti S, Li Y, Chai HS, Sun Z, Duffy PH, Hadad AA, Nair A, Liu X, Zhang Y, Klee EW, Kalari KR, Kocher JP.
Bioinformatics. 2012 Jan 15;28(2):277-8. Epub 2011 Nov 15.