TREAT (TREe-based Association Test) version 0.0.5 is an R package for detecting complex joint effects in case-control studies. The test statistic is derived from a tree-structure model by recursive partitioning the data. Ultra-fast algorithm is designed to evaluate the significance of association between candidate gene and disease outcome.
- R package
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Bioinformatics. 2014 May 2. [Epub ahead of print]
A fast and powerful tree-based association test for detecting complex joint effects in case-control studies.
Zhang H1, Wheeler W, Wang Z, Taylor PR, Yu K.