TOPSPOT is a software which has been developed for the purpose of analysing 2-dimensional electrophoretic imaging (2DE) of gels. It enables the user to obtain qualitative and quantitative gel data from gel images available in a BMP format or obtained using a scanner. The development of the program entailed close co-operation between two institutes in Berlin, where the 2-dimensional electrophoresis was carried out. As a result, the structure and function of TOPSPOT have been shaped by the requirements of the 2DE laboratory. Statistical comparisons of gel data and the construction of a 2DE database can be carried out using conventional statistical and database programs, since all relevant TOPSPOT gel data are available in the ASCII format.
Algorithmus, Prehm Berlin
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High-performance human myocardial two-dimensional electrophoresis database: edition 1996.
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