Tomcat tests for association between genetic markers and phenotypes in case-control studies using haplotype information. The potential value of haplotypes has attracted widespread interest in the mapping of complex traits. Haplotype sharing methods take linkage disequilibrium information between multiple markers into account, and may have good power to detect predisposing genes.
Division of Cancer Epidemiology, German Cancer Research Center
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Hum Hered. 2005;59(2):67-78. Epub 2005 Apr 18.
Haplotype sharing analysis using mantel statistics.
Beckmann L, Thomas DC, Fischer C, Chang-Claude J.