TINKER is a metabolic pathway design/search tool. It compiles the entire set of known reactions and compounds from the latest version of the Rhea database and converts this data into a directed graph
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Metabolic tinker: an online tool for guiding the design of synthetic metabolic pathways.
McClymont K, Soyer OS.
Nucleic Acids Res. 2013 Jun;41(11):e113. doi: 10.1093/nar/gkt234.