TBC assigns similar sequences to operational taxonomic units, or OTUs, by clustering sequences based on a user-defined similarity threshold. Sequences that are similar at or above the threshold level are taken to represent the presence of a taxonomic unit (e.g., a species, when the similarity threshold is set at 0.97) in the sequence collection.
The Jongsik Chun Lab. and Chunlab, Inc.
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J Microbiol. 2012 Apr;50(2):181-5. doi: 10.1007/s12275-012-1214-6. Epub 2012 Apr 27.
TBC: a clustering algorithm based on prokaryotic taxonomy.
Lee JH, Yi H, Jeon YS, Won S, Chun J.