TAXFOLD is a new taxonomy-based protein fold recognition method. It extensively exploits the sequence evolution information from PSI-BLAST profiles and the secondary structure information from PSIPRED profiles. A comprehensive set of 137 features is constructed, which allows for the depiction of both global and local characteristics of PSI-BLAST and PSIPRED profiles.
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Jian-Yi Yang and Xin Chen,
Improving taxonomy-based protein fold recognition by using global and local features,
Proteins: Structure, Function, and Bioinformatics Volume 79, Issue 7, pages 2053–2064, July 2011