SpotOn – Determination of Hot-Spots at Protein-protein interfaces

SpotOn

:: DESCRIPTION

SpotOn is a robust algorithm developed to identify and classify the interfacial residues as Hot-Spots (HS) and Null-Spots (NS) with a final accuracy of 0.95 and a sensitivity of 0.95 on an independent test set.

::DEVELOPER

BONVIN LAB

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots.
Moreira IS, et al.
Sci Rep, 7 (1), 8007 2017 Aug 14

WHISCY 1.02 – Predict Protein-protein Interfaces

WHISCY 1.02

:: DESCRIPTION

WHISCY (What information does surface conservation yield?) is a program to predict protein-protein interfaces. It is primarily based on conservation, but it also takes into account structural information. A sequence alignment is used to calculate a prediction score for each surface residue of your protein.

::DEVELOPER

BONVIN LAB

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

De Vries SJ, van Dijk ADJ, and Bonvin AMJJ
WHISCY: What information does surface conservation yield? Application to data-driven docking.
Proteins: Struc. Funct. & Bioinformatics; 2006, 63(3): 479-489.