SIBLINK 3.0 – Multipoint Linkage Analysis

SIBLINK 3.0

:: DESCRIPTION

SIBLINK allows the user to perform multipoint linkage analysis based on estimated IBD sharing between affected sibpairs. IBD sharing is inferred from IBS status, given marker genotypes, frequencies, and locations. Resulting LOD scores are maximized across a grid of possible disease locations and IBD sharing vectors.

::DEVELOPER

Duke Molecular Physiology Institute

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Solaris 7 (or higher)

:: DOWNLOAD

 SIBLINK

:: MORE INFORMATION

Citation

Shah SH, Schmidt MA, Mei H, Scott WK, Hauser ER, Schmidt S.
Searching for epistatic interactions in nuclear families using conditional linkage analysis.
BMC Genet. 2005 Dec 30;6 Suppl 1:S148.

SIMPLE – Sequential Imputation for MultiPoint Linkage Estimation

SIMPLE

:: DESCRIPTION

SIMPLE (Sequential Imputation for MultiPoint Linkage Estimation) is a software to calculate linkage statistics, such as lod scores and NPL statistics by Sequential Imputation.

::DEVELOPER

Statistical Genetics and Bioinformatics Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 SIMPLE

:: MORE INFORMATION

Citation

Lin, S., Skrivanek, Z., Irwin, M. (2003)
Haplotying using SIMPLE – caution on ignoring interference.
Genetic Epidemiology, 25:384-387

MULTIDISEQ – Multipoint Linkage Analysis software which allows Marker-Marker LD

MULTIDISEQ

:: DESCRIPTION

MULTIDISEQ is multipoint linkage analysis software which allows Marker-Marker LD.

::DEVELOPER

Joseph D. Terwilliger and Alejandro Schäffer

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 MULTIDISEQ

:: MORE INFORMATION

Citation:

T Hiekkalinna, L Peltonen1, JD Terwilliger (2003),
“MULTIDISEQ: Computer software for multipoint linkage analysis of complex traits allowing for marker-marker LD (Linkage Disequilibrium)”
American Journal of Human Genetics, suppl, 73