MIMP – Predicting the Impact of Mutations on Kinase-substrate Phosphorylation

MIMP

:: DESCRIPTION

MIMP characterizes genetic variants such as cancer mutations that specifically alter kinase-binding sites in proteins.

::DEVELOPER

Bader Lab University of Toronto

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser / Linux
  • R

:: DOWNLOAD

MIMP

:: MORE INFORMATION

Citation

MIMP: predicting the impact of mutations on kinase-substrate phosphorylation.
Wagih O, Reimand J, Bader GD.
Nat Methods. 2015 Jun;12(6):531-3. doi: 10.1038/nmeth.3396.

SPIA 2.22.0 – Signaling Pathway Impact Analysis

SPIA 2.22.0

:: DESCRIPTION

SPIA is a standard Bioconductor style R package designed to perform pathway analysis using over representation evidence and pathway topology information.

::DEVELOPER

the Bioinformatics and Computational Biology Unit of the Perinatology Research Branch (NICHD)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / MacOS
  • R package
  • Bioconductor

:: DOWNLOAD

 SPIA

:: MORE INFORMATION

Citation

Bioinformatics. 2009 Jan 1;25(1):75-82. doi: 10.1093/bioinformatics/btn577. Epub 2008 Nov 5.
A novel signaling pathway impact analysis.
Tarca AL, Draghici S, Khatri P, Hassan SS, Mittal P, Kim JS, Kim CJ, Kusanovic JP, Romero R.