GPCRpred – Prediction of Families & Superfamilies of G-protein Coupled receptors

GPCRpred

:: DESCRIPTION

 GPCRpred is a server forpredicting G-protein-coupled receptors and for classifying them in families and sub-families. This server can play vital role in drug design, as GPCR are commonly used as drug targets

::DEVELOPER

GPCRpred Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Bhasin,M. and Raghava, G.P.S. (2004)
GPCRpred: An SVM Based Method for Prediction of families and subfamilies of G-protein coupled receptors.
Nucleic Acids Reasearch.Vol. 32. W383-W389

GPCR-ModSim – Computational Modeling and Simulation of G-Protein Coupled Receptors

GPCR-ModSim

:: DESCRIPTION

GPCR-ModSim is a centralized and easy to use service dedicated to the structural modeling of G-protein Coupled Receptors (GPCRs).

::DEVELOPER

GPCR-ModSim team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

GPCR-ModSim: A comprehensive web based solution for modeling G-protein coupled receptors.
Esguerra M, Siretskiy A, Bello X, Sallander J, Gutiérrez-de-Terán H.
Nucleic Acids Res. 2016 May 10. pii: gkw403.

GprotPRED – Detection of distinct Galpha families, Gbeta and Ggamma subunits of heterotrimeric G-proteins

GprotPRED

:: DESCRIPTION

GprotPRED is an online tool that uses profile Hidden Markov Models (pHMMs) for the four known heterotrimeric Galpha protein families, the Gbeta and the Ggamma subunit in order to classify a set of protein sequences into the appropriate G-protein family.

::DEVELOPER

The Biophysics and Bioinformatics Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Perl

:: DOWNLOAD

GprotPRED

:: MORE INFORMATION

Citation

Biochim Biophys Acta. 2016 May;1864(5):435-40. doi: 10.1016/j.bbapap.2016.02.005. Epub 2016 Feb 5.
GprotPRED: Annotation of Gα, Gβ and Gγ subunits of G-proteins using profile Hidden Markov Models (pHMMs) and application to proteomes.
Kostiou VD, Theodoropoulou MC, Hamodrakas SJ.