EpiPred – B-cell Epitope Prediction

EpiPred

:: DESCRIPTION

EpiPred is a software of B-cell epitope prediction and antibody-antigen docking

::DEVELOPER

Oxford Protein Informatics Group (OPIG)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • JRE
  • Python

:: DOWNLOAD

 EpiPred

:: MORE INFORMATION

Citation:

Improving B-cell epitope prediction and its application to global antibody-antigen docking.
Krawczyk K, Liu X, Baker T, Shi J, Deane CM.
Bioinformatics. 2014 Aug 15;30(16):2288-94. doi: 10.1093/bioinformatics/btu190.

CTLPred – SVM & ANN Based CTL epitope Prediction method

CTLPred

:: DESCRIPTION

CTLPred is a direct method for prediction of CTL epitopes crucial in subunit vaccine design.In direct methods the information or patterns of T cell epitopes instead of MHC binders were used for the development o f methods. The methods is based on elegant machine learning techniques like a Artificial Neural network and support vector machine .

::DEVELOPER

CTLPred Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Bhasin,M. and Raghava, G.P.S. (2004)
Prediction of CTL epitopes using QM, SVM and ANN techniques.
Vaccine,22,3195-3201.

ABCpred – Artificial Neural Network based B-cell Epitope Prediction Server

ABCpred

:: DESCRIPTION

ABCpred server is to predict linear B cell epitope regions in an antigen sequence, using artificial neural network. This server will assist in locating epitope regions that are useful in selecting synthetic vaccine candidates, disease diagonosis and also in allergy research.

::DEVELOPER

ABCpred Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Saha, S and Raghava G.P.S. (2006)
Prediction of Continuous B-cell Epitopes in an Antigen Using Recurrent Neural Network.
Proteins,65(1),40-48

BcePred – Predict B cell Epitope based on Physio-chemical Properties of Amino Acids

BcePred

:: DESCRIPTION

The BcePred server predicts B cell epitope based on physio-chemical properties of amino acids.

::DEVELOPER

BcePred Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Saha.S and Raghava G.P.S.
BcePred:Prediction of Continuous B-Cell Epitopes in Antigenic Sequences Using Physico-chemical Properties.
In G.Nicosia, V.Cutello, P.J. Bentley and J.Timis (Eds.) ICARIS 2004, LNCS 3239, 197-204, Springer,2004.

CBTOPE – Conformational B-cell Epitope Prediction

CBTOPE

:: DESCRIPTION

CBTOPE server discriminate the antibody epitope residues and non-epitope residues for a given protein sequence.

::DEVELOPER

CBTOPE team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 CBTOPE

:: MORE INFORMATION

Citation

Immunome Res. 2010 Oct 20;6:6. doi: 10.1186/1745-7580-6-6.
Identification of conformational B-cell Epitopes in an antigen from its primary sequence.
Ansari HR1, Raghava GP.

IFNepitope – Predicting and Designing Interferon-gamma inducing Epitopes

IFNepitope

:: DESCRIPTION

IFNepitope is a web server to predict and design the epitope, which could induce the release of interferon gamma. The webserver has been developed on the basis of a dataset, which comprises of IFN-gamma inducing and non-inducing MHC class II binders.

::DEVELOPER

IFNepitope team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Biol Direct. 2013 Dec 5;8:30. doi: 10.1186/1745-6150-8-30.
Designing of interferon-gamma inducing MHC class-II binders.
Dhanda SK1, Vir P, Raghava GP.

TepiTool – Computational Prediction of T Cell Epitope Candidates

TepiTool

:: DESCRIPTION

The Tepitool provides prediction of peptides binding to MHC class I and class II molecules.

::DEVELOPER

the IEDB Solutions Center

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 TepiTool

:: MORE INFORMATION

Citation

TepiTool: A Pipeline for Computational Prediction of T Cell Epitope Candidates.
Paul S, Sidney J, Sette A, Peters B.
Curr Protoc Immunol. 2016 Aug 1;114:18.19.1-18.19.24. doi: 10.1002/cpim.12.

EPISOFT – Epitope Vaccine Optimization Server

EPISOFT

:: DESCRIPTION

EPISOFT predicts epitope HLA I binding profiles and computes population protection (PPC). It also identifies minimal sets of epitopes that reach a target PPC for 5 distinct user-selected ethnic groups.

::DEVELOPER

Immunomedicine Group 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation:

Towards the Knowledge-based Design of Universal Influenza Epitope Ensemble Vaccines.
Sheikh QM, Gatherer D, Reche PA, Flower DR.
Bioinformatics. 2016 Jul 10. pii: btw399.

ProInflam – Prediction of Proinflamatory Epitopes

ProInflam

:: DESCRIPTION

ProInflam is a webserver for the prediction of proinflammatory antigenicity of peptides and proteins.

::DEVELOPER

MetaBioSys laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

ProInflam: a webserver for the prediction of proinflammatory antigenicity of peptides and proteins.
Gupta S, Madhu MK, Sharma AK, Sharma VK.
J Transl Med. 2016 Jun 14;14(1):178. doi: 10.1186/s12967-016-0928-3.

EPI-Peptide Designer – Designing Specific Peptide Ligand Libraries based on Epitope-Paratope Interactions

EPI-Peptide Designer

:: DESCRIPTION

EPI-Peptide Designer tool predicted paratope residues for an epitope of interest to generate targeted peptide ligand libraries.

::DEVELOPER

the Protein Computational Biology group.

:: SCREENSHOTS

EPI-Peptide

:: REQUIREMENTS

  • Linux/ Windows
  • Java

:: DOWNLOAD

 EPI-Peptide Designer

:: MORE INFORMATION

Citation

EPI-Peptide Designer : a tool for designing specific peptide ligand libraries based on Epitope-Paratope Interactions.
Viart B, Gonzalez E, Dias-Lopes C, Oliveira CF, Nguyen C, Neshich G, Chávez-Olórtegui C, Molina F, Felicori L.
Bioinformatics. 2016 Jan 18. pii: btw014.