Structured Input-output Lasso – Leveraging input and output Structures for Joint Mapping of Epistatic and Marginal eQTLs

Structured Input-output Lasso

:: DESCRIPTION

Structured Input-output Lasso is a novel regularization scheme over multitask regression , which allows shared sparsity patterns for related inputs and outputs to be optimally estimated.  Such patterns capture multiple related single nucleotide polymorphisms (SNPs) that jointly influence multiple-related expression traits.

::DEVELOPER

the SAILING lab (the Laboratory of Statistical Artificial InteLligence and INtegrative Genomics)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • Matlab

:: DOWNLOAD

  Structured Input-output Lasso

:: MORE INFORMATION

Citation

Seunghak Lee and Eric P. Xing
Leveraging Input and Output Structures For Joint Mapping of Epistatic and Marginal eQTLs
Bioinformatics (2012) 28 (12): i137-i146.

QTLNETWORK 2.1 – Map QTL with Epistatic and QE interaction effects in Experimental Populations

QTLNETWORK 2.1

:: DESCRIPTION

QTLNetwork is a software package for mapping and visualizing the genetic architecture underlying complex traits for experimental populations derived from a cross between two inbred lines.

::DEVELOPER

ZJU-IBI

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux/windows/MacOsX

:: DOWNLOAD

 QTLNETWORK

:: MORE INFORMATION

Citation

Yang, Hu, Hu, Yu, Xia, Ye, Zhu (2008),
QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations“,
Bioinformatics. 24(5):721-723.