QuickES is a wrapper program for the Ecotype Simulation Algorithm that can predict ecotypes based on DNA sequences alone. QuickES sacrifices some of the precision of the complete algorithm in exchange for dramatically increased speed.
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Nucleic Acids Res. 2013 May 1;41(10):5175-88. doi: 10.1093/nar/gkt241. Epub 2013 Apr 9.
Surprisingly extensive mixed phylogenetic and ecological signals among bacterial Operational Taxonomic Units.
Koeppel AF1, Wu M.