Blogo is a web-based tool that detects and displays statistically significant position-specific sequence bias with reduced background noise. The over-represented and under-represented symbols in a particular position are shown above and below the zero line. When the sequences are in open reading frames, the background frequency of nucleotides could be calculated separately for the three positions of a codon, thus greatly reducing the background noise.
Dr. Wencheng Li (email email@example.com).
- Linux / Windows / Mac OsX
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Li W, Yang B, Liang S, Wang Y, Whiteley C, Cao Y, Wang X. (2008)
BLogo: A tool for visualization of bias in biological sequences.
Bioinformatics doi: 10.1093/bioinformatics/btn407.