TAFFEL implements a novel method called Independent Enrichment Analysis (IEA) and eases the task by clustering genes to subgroups using Gene Ontology categories and transcription regulators.TAFFEL can be used to analyze gene lists in order to find separate gene subgroups that are coregulated by the same transcription factors or carry out the same biological function, and perform comparison of correlation between co-regulation and co-function with these gene subsets.
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BMC Bioinformatics. 2011 May 19;12:171. doi: 10.1186/1471-2105-12-171.
TAFFEL: Independent Enrichment Analysis of gene sets.
Kurki MI1, Paananen J, Storvik M, Ylä-Herttuala S, Jääskeläinen JE, von Und Zu Fraunberg M, Wong G, Pehkonen P.