SymmRef is a method for refinement and re-ranking of symmetric docking solutions, with Cn symmetry. The method models backbone and side-chain movements and optimizes the rigid-body orientations of the monomers. The backbone movements are modeled by normal modes minimization and the conformations of the side-chains are modeled by selecting optimal rotamers.
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Efrat Mashiach-Farkash, Ruth Nussinov and Haim J. Wolfson.
SymmRef: A flexible refinement method for symmetric multimers .
Proteins: Structure, Function, and Bioinformatics Volume 79, Issue 9, pages 2607–2623, September 2011