Dec 032012
 

StatSigMA beta / StatSigMA-w v2

:: DESCRIPTION

StatSigMA (Statistical Significance of Multiple Alignments) computes the statistical significance of multiple sequence alignments (of either nucleotide or amino acid sequences), much as BLAST’s E-values provide statistical significance for pairwise alignments.

StatSigMA-w (Statistical Significance of Whole-Genome Multiple Alignments),Given any multiple sequence alignment and a phylogeny of the aligned sequences, assesses the accuracy of the alignment and identifies suspiciously aligned regions.

::DEVELOPER

The Computational & Synthetic Biology group – COMPUTER SCIENCE & ENGINEERING at UNIVERSITY OF WASHINGTON

:: SCREENSHOTS

Command Line

:: REQUIREMENTS

:: DOWNLOAD

StatSigMA , StatSigMA-w

:: MORE INFORMATION

Citation:

A. Prakash, M. Tompa,
Assessing the discordance of multiple sequence alignments“,
IEEE/ACM Trans Comput Biol Bioinform, vol. 6 (2009) 542-51.Pubmed 19875854.

X. Chen, M. Tompa,
Comparative assessment of methods for aligning multiple genome sequences“,
Nat. Biotechnol., vol. 28 (2010) 567-72.

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