Mar 062015
 

Spotlite

:: DESCRIPTION

Spotlite is a user-friendly web application for predicting complex co-membership from affinity purification – mass spectrometry data. This web application employs a logistic regression classifier that integrates existing, proven APMS scoring approaches (SAINT, CompPASS, and HGSCore), gene co-expression patterns, functional annotations, domain-domain binding affinity, and homologous interactions, which we have shown outperforms existing APMS scoring methods.

::DEVELOPER

Major Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

J Proteome Res. 2014 Dec 5;13(12):5944-55. doi: 10.1021/pr5008416. Epub 2014 Oct 20.
Spotlite: web application and augmented algorithms for predicting co-complexed proteins from affinity purification–mass spectrometry data.
Goldfarb D1, Hast BE, Wang W, Major MB.

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