SPEPlip is a neural network-based method, trained and tested on a set of experimentally derived signal peptides from eukaryotes and prokaryotes. SPEPlip identifies the presence of sorting signals and predicts their cleavage sites.
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Bioinformatics. 2003 Dec 12;19(18):2498-9.
SPEPlip: the detection of signal peptide and lipoprotein cleavage sites.
Fariselli P, Finocchiaro G, Casadio R.