Spectrum is a program for jointly inferring population structure and recombination events using multi-locus SNP haplotypes. Assuming a number of founder chromosomes, it infers the association of each individual with founders and generates an ancestral spectrum, which displays genetic population structure and reveals details of the genetic diversity of each individual with respect to recovered founder chromosomes. It also estimates empirical recombination rates and hotspots jointly with the population structure.
the SAILING lab (the Laboratory of Statistical Artificial InteLligence and INtegrative Genomics)
- Linux / Windows
:: MORE INFORMATION
Kyung-Ah Sohn and Eric P. Xing,
Spectrum:Joint Bayesian Inference of Population Structure and Recombination Events.
Bioinformatics. 2007 Jul 1;23(13):i479-89.