SNPdetector is a software for automated identification of SNPs and mutations in fluorescence-based resequencing reads. SNPdetector was designed to model the process of human visual inspection and has a very low false positive and false negative rate. We demonstrate the superior performance of SNPdetector in SNP and mutation analysis by comparing its results with those derived by human inspection, PolyPhred (a popular SNP detection tool), and independent genotype assays in three large-scale investigations.
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Zhang J, Wheeler DA, Yakub I, Wei S, Sood R, et al. (2005)
SNPdetector: A Software Tool for Sensitive and Accurate SNP Detection.
PLoS Comput Biol 1(5): e53.