SNOMAD is a program for the standardization and normalization of gene expression datasets. In addition to conventional transformations and visualization tools, SNOMAD includes two non-linear transformations which correct for bias and variance which are non-uniformly distributed across the range of microarray element signal intensities: local mean normalization and local variance correction (Z-score generation using a locally calculated standard deviation).
- Linux / Windows/ MacOsX
- R package
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Bioinformatics. 2002 Nov;18(11):1540-1.
SNOMAD (Standardization and NOrmalization of MicroArray Data): web-accessible gene expression data analysis.
Colantuoni C, Henry G, Zeger S, Pevsner J.