Jan 162014
 

Sleipnir 3.0 / COALESCE

:: DESCRIPTION

Sleipnir is a C++ library enabling efficient analysis, integration, mining, and machine learning over genomic data. This includes a particular focus on microarrays, since they make up the bulk of available data for many organisms, but Sleipnir can also integrate a wide variety of other data types, from pairwise physical interactions to sequence similarity or shared transcription factor binding sites.

COALESCE (Combinatorial Algorithm for Expression and Sequence-based Cluster Extraction) can use large collections of genomic data and Bayesian integration to predict coregulated gene modules, the conditions of regulation, and the consensus binding motifs for regulation.

::DEVELOPER

Laboratory for Bioinformatics and Functional Genomics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux
  • C Compiler

:: DOWNLOAD

 Sleipnir

:: MORE INFORMATION

Citation

Curtis Huttenhower, Mark Schroeder, Maria D. Chikina, and Olga G. Troyanskaya
The Sleipnir library for computational functional genomics”,
Bioinformatics. 2008 Jul 1;24(13):1559-61. Epub 2008 May 21.

Bioinformatics. 2009 Dec 15;25(24):3267-74. doi: 10.1093/bioinformatics/btp588.
Detailing regulatory networks through large scale data integration.
Huttenhower C, Mutungu KT, Indik N, Yang W, Schroeder M, Forman JJ, Troyanskaya OG, Coller HA.

327 views

Sorry, the comment form is closed at this time.