SIFT 5.2.2 – Amino Acid Substitution Affects Protein Function

SIFT 5.2.2

:: DESCRIPTION

SIFT (Sorting Intolerant From Tolerant) is a program for predicting whether an amino acid substitution affects protein function, based on sequence homology and the physical properties of amino acids. It is one of several programs using sequence information for this purpose.

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::DEVELOPER

Fred Hutchinson Cancer Research Center

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

  SIFT

:: MORE INFORMATION

Citation:

Ng PC, Henikoff S. 2002.
Accounting for human polymorphisms predicted to affect protein function.
Genome Research 12:436-446. doi:10.1101/gr.212802

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