SIBMED 1.0 – Identify Likely Genotyping Errors and Mutations

SIBMED 1.0

:: DESCRIPTION

SIBMED ((SIBpair Mutation and Error Detection)) is a FORTRAN 77 program that identifies likely genotyping errors and mutations for a sib pair in the context of multipoint mapping.Specifically, using a hidden Markov model, the program calculates the posterior probability of genotyping error or mutation for each sib-pair-marker combination, given all the available marker data, an assumed genotype-error rate, and a known genetic map.  The subset of combinations for which this posterior error probability is high may be considered for exclusion, review, or retyping.

::DEVELOPER

the Center for Statistical Genetics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Mac OsX / Windows
  • FORTRAN

:: DOWNLOAD

  SIBMED

:: MORE INFORMATION

Citation

Douglas JA, Boehnke M, Lange K (2000)
A multipoint method for detecting genotyping errors and mutations in sibling-pair linkage data.
Am J Hum Genet 66: 1287-1297

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