SIBLINK 3.0 – Multipoint Linkage Analysis

SIBLINK 3.0

:: DESCRIPTION

SIBLINK allows the user to perform multipoint linkage analysis based on estimated IBD sharing between affected sibpairs. IBD sharing is inferred from IBS status, given marker genotypes, frequencies, and locations. Resulting LOD scores are maximized across a grid of possible disease locations and IBD sharing vectors.

::DEVELOPER

Duke Molecular Physiology Institute

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Solaris 7 (or higher)

:: DOWNLOAD

 SIBLINK

:: MORE INFORMATION

Citation

Shah SH, Schmidt MA, Mei H, Scott WK, Hauser ER, Schmidt S.
Searching for epistatic interactions in nuclear families using conditional linkage analysis.
BMC Genet. 2005 Dec 30;6 Suppl 1:S148.

Leave a Reply

Your email address will not be published. Required fields are marked *

 

This site uses Akismet to reduce spam. Learn how your comment data is processed.