The SHERA software turns error-prone short reads into Sanger-quality composite reads by aligning the overlapping ends of each matepair. Given a library of appropriately-sized inserts, paired-end reads of each insert overlap in the middle, and can be aligned to produce a longer, more accurate composite read, extending the scope of applications for high throughput shortread sequencing.
- Windows / Linux / Mac OsX
:: MORE INFORMATION
Rodrigue S, Materna AC, Timberlake SC, Blackburn MC, Malmstrom RR, et al. (2010)
Unlocking Short Read Sequencing for Metagenomics.
PLoS ONE 5(7): e11840. doi:10.1371/journal.pone.0011840