Seqool is a free (for educational use) sequence analysis software designed primarily for searching biological signals in nucleic acid sequences. The sequence analysis program package provides several pattern recognition models, but it also includes the most common sequence analysis statistics, such as GC content, codon usage, etc.
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Wang, M. 2011.
Seqool – A sequence analysis tool for signal search, pattern recognition and sequence statistics. Version 3.1,
available at: http://biossc.de/seqool.