Seal is a suite of distributed applications for aligning short DNA reads, and manipulating and analyzing short read alignments. Seal applications generally run on the Hadoop framework and are made to scale well in the amount of computing nodes available and the amount of the data to process. This fact makes Seal particularly well suited for processing large data sets. Seal is part of the Biodoop suite of tools.
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Bioinformatics. 2011 Aug 1;27(15):2159-60. doi: 10.1093/bioinformatics/btr325.
SEAL: a distributed short read mapping and duplicate removal tool.
Pireddu L, Leo S, Zanetti G.