Samscope is a lightweight SAM/BAM file viewer that makes visually exploring next generation sequencing data intuitive and maybe even fun!Samscope uses multiple layers to simultaneously (or sequentially) view SAM/BAM related features like coverage or allele frequency, or ChIP-SEQ features like polarity. The paging-friendly binary file layout makes it feasible to browse data sets far larger than the system’s available RAM.
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Bioinformatics. 2012 May 1;28(9):1276-7. doi: 10.1093/bioinformatics/bts122. Epub 2012 Mar 13.
SAMSCOPE: an OpenGL-based real-time interactive scale-free SAM viewer.
Popendorf K, Sakakibara Y.