Aug 202013
 

SAMPLE 20090428

:: DESCRIPTION

SAMPLE is designed to identify regions that are linked to a recessive disease by analysing genotype data from the parents and unaffected sibs of affected individuals. Since this analysis does not use data from affected patients, it is suited to the identification of lethal recessive genes, when the patients may have died before DNA samples could be obtained.

::DEVELOPER

Leeds Institute of Molecular Medicine

:: SCREENSHOTS

SAMPLE

:: REQUIREMENTS

  • Windows
  • Microsoft .NET framework version 2.0 

:: DOWNLOAD

 SAMPLE

:: MORE INFORMATION

Citation

Carr IM, Szymanska K, Sheridan E, Markham AF, Bonthron DT, Johnson CA (2009).
Shadow autozygosity mapping by linkage exclusion (SAMPLE): a simple strategy to identify the genetic basis of lethal autosomal recessive disorders.
Hum Mutat 30: 1642-1649.

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