S-Peaker uses the Annotation-Supported model to identify probable locations for single-peak TSSs (transcription start sites) in an input sequence. Specifically, one can provide a FASTA sequence to the tool and obtain a UCSC custom track that displays the probability of observing a Single-Peak TSS at each position in the sequences
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Megraw M, Pereira F, Jensen ST, Ohler U, Hatzigeorgiou AG. (2009).
A transcription factor affinity based code for mammalian transcription initiation.
Genome Research, 19:644-56.