rSW-seq – Detection of Copy Number Alterations in Deep Sequencing data

rSW-seq

:: DESCRIPTION

rSW-seq is designed to identify copy number alterations between tumor-vs-matched normal genomes (or between normal-vs-normal genomes for CNV detection) from deep sequencing data generated by next-generation sequencing.  Compared to other algorithms (BreakDancer or MoDIL) using PEM (paired-end mapping) signatures, rSW-seq uses ‘read-depth’ as primary measure, which can be applied to single-end sequencing read set.

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::DEVELOPER

Tae-Min Kim. , Peter J.Park

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows

:: DOWNLOAD

 rSW-seq

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2010 Aug 18;11:432.
rSW-seq: algorithm for detection of copy number alterations in deep sequencing data.
Kim TM, Luquette LJ, Xi R, Park PJ.

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