RnBeads is the first software tool that implements a comprehensive workflow for analyzing DNA methylation data in the context of large cohort studies. Its functionality comprises data normalization, quality control, probe and sample filtering, handing of batch effects, global DNA methylation analysis, detection of differentially methylated regions and interpretation by statistical enrichment analysis.
- R package
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Comprehensive analysis of DNA methylation data with RnBeads.
Assenov Y, Müller F, Lutsik P, Walter J, Lengauer T, Bock C.
Nat Methods. 2014 Sep 28. doi: 10.1038/nmeth.3115.