Feb 292012
 

RNApathfinder

:: DESCRIPTION

RNApathfinder is a web server to compute near-optimal folding pathways between two given secondary structures for a given RNA sequence. Since this problem is known to be NP-complete, our main algorithm, RNAtabupath uses the TABU local search heuristic. The web server includes both downloadable source code for several algorithms, as well as a web engine to compute pathways. Intended applications concern folding pathways for RNA conformational switches.

::DEVELOPER

Clote Lab 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  Mac OsX / Windows
  • WebServer
  • Python

:: DOWNLOAD

 RNApathfinder

:: MORE INFORMATION

Citation:

I. Dotú, W.A. Lorenz, P. Van Hentenryck, P. Clote.
Computing folding pathways between RNA secondary structures.
Nucleic Acids Res. 2010 Mar 1;38(5):1711-22.

359 views

Sorry, the comment form is closed at this time.