RFMix is a powerful discriminative modeling approach that is faster (~30×) and more accurate than existing methods.RFMix is capable of learning from the admixed samples themselves to boost performance and autocorrect phasing errors. RFMix shows high sensitivity and specificity in simulated Hispanics/Latinos and African Americans and admixed Europeans, Africans, and Asians.
- R package
:: MORE INFORMATION
Am J Hum Genet. 2013 Aug 8;93(2):278-88. doi: 10.1016/j.ajhg.2013.06.020. Epub 2013 Aug 1.
RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference.
Maples BK1, Gravel S, Kenny EE, Bustamante CD.