PyClone 0.13.1 – Infer Clonal Frequency Estimates of a Panel of deeply Sequenced Mutations

PyClone 0.12.7

:: DESCRIPTION

 pyClone is a software used to infer clonal frequency estimates of a panel of deeply sequenced mutations. The software is a Bayesian hierachical model for inferring the frequency of cells with a given mutation from allelic count data generated by next generation sequencing experiments. PyClone makes use of prior information about genotype as well as jointly analysing all mutations in a sample.

postpy is a set of tools to help with post-processing PyClone results.

::DEVELOPER

Shah Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows
  • Python

:: DOWNLOAD

 PyClone, postpy

:: MORE INFORMATION

Citation

Sohrab P. Shah et al.
The clonal and mutational evolution spectrum of primary triple-negative breast cancers”.
Nature 486, 395–399 (21 June 2012)
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