Sep 292013
 

Filtering False Somatic Mutations from FFPE Tumor Sequencing data

:: DESCRIPTION

This program suite consists of 4 PERL programs made to identify and remove potential false positive somatic variants caused by FFPE (formalin-fixed paraffin-embedded) DNA damage on next-generation sequencing data.

::DEVELOPER

the Division of Genome Information Sciences, UCSD

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ WIndows/ MacOsX
  • Perl

:: DOWNLOAD

 program suite

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2012 Aug;40(14):e107. Epub 2012 Apr 6.
Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens.
Yost SE, Smith EN, Schwab RB, Bao L, Jung H, Wang X, Voest E, Pierce JP, Messer K, Parker BA, Harismendy O, Frazer KA.

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